Photoflow is a new native application to enjoy Instagram on your Apple Mac. This is a fully-featured application that lets you navigate your feed via your magic mouse or trackpad, search for images and users, as well as offering the ability to manage multiple Instagram accounts.
Of course you can favourite images and follow new users, the only real missing functionality is the ability to upload new images to your accounts. This is due to a limitation with the API though, so the app developers cannot be faulted for this.
Visit Photoflow to find out more.